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BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint., Swaminathan, Srividya, Huang ChuanXin, Geng Huimin, Chen Zhengshan, Harvey Richard, Kang Huining, Ng Carina, Titz Björn, Hurtz Christian, Sadiyah Mohammed Firas, et al. , Nat Med, 2013 Aug, Volume 19, Issue 8, p.1014-22, (2013)
A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis., Sun, Xiao-Jian, Wang Zhanxin, Wang Lan, Jiang Yanwen, Kost Nils, T Soong David, Chen Wei-Yi, Tang Zhanyun, Nakadai Tomoyoshi, Elemento Olivier, et al. , Nature, 2013 Aug 01, Volume 500, Issue 7460, p.93-7, (2013)
Meta-analysis of microarray studies reveals a novel hematopoietic progenitor cell signature and demonstrates feasibility of inter-platform data integration., Sohal, Davendra, Yeatts Andrew, Ye Kenny, Pellagatti Andrea, Zhou Li, Pahanish Perry, Mo Yongkai, Bhagat Tushar, Mariadason John, Boultwood Jacqueline, et al. , PLoS One, 2008 Aug 13, Volume 3, Issue 8, p.e2965, (2008)
Molecular pathogenesis of acute promyelocytic leukaemia and APL variants., Sirulnik, Andres, Melnick Ari, Zelent Arthur, and Licht Jonathan D. , Best Pract Res Clin Haematol, 2003 Sep, Volume 16, Issue 3, p.387-408, (2003)
Erk Negative Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia., Shojaee, Seyedmehdi, Caeser Rebecca, Buchner Maike, Park Eugene, Swaminathan Srividya, Hurtz Christian, Geng Huimin, Chan Lai N., Klemm Lars, Hofmann Wolf-Karsten, et al. , Cancer Cell, 2015 Jul 13, Volume 28, Issue 1, p.114-28, (2015)
PTEN opposes negative selection and enables oncogenic transformation of pre-B cells., Shojaee, Seyedmehdi, Chan Lai N., Buchner Maike, Cazzaniga Valeria, Cosgun Kadriye Nehir, Geng Huimin, Qiu Yi Hua, von Minden Marcus Dühren, Ernst Thomas, Hochhaus Andreas, et al. , Nat Med, 2016 Apr, Volume 22, Issue 4, p.379-87, (2016)
Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in - and -Mutant Acute Myeloid Leukemia., Shih, Alan H., Meydan Cem, Shank Kaitlyn, Garrett-Bakelman Francine E., Ward Patrick S., Intlekofer Andrew M., Nazir Abbas, Stein Eytan M., Knapp Kristina, Glass Jacob, et al. , Cancer Discov, 2017 05, Volume 7, Issue 5, p.494-505, (2017)
Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia., Shih, Alan H., Jiang Yanwen, Meydan Cem, Shank Kaitlyn, Pandey Suveg, Barreyro Laura, Antony-Debre Ileana, Viale Agnes, Socci Nicholas, Sun Yongming, et al. , Cancer Cell, 2015 Apr 13, Volume 27, Issue 4, p.502-15, (2015)
DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation., Shaknovich, Rita, Cerchietti Leandro, Tsikitas Lucas, Kormaksson Matthias, De Subhajyoti, Figueroa Maria E., Ballon Gianna, Yang Shao Ning, Weinhold Nils, Reimers Mark, et al. , Blood, 2011 Sep 29, Volume 118, Issue 13, p.3559-69, (2011)
HELP (HpaII tiny fragment enrichment by ligation-mediated PCR) assay for DNA methylation profiling of primary normal and malignant B lymphocytes., Shaknovich, Rita, Figueroa Maria E., and Melnick Ari , Methods Mol Biol, 2010, Volume 632, p.191-201, (2010)
DNA methylation signatures define molecular subtypes of diffuse large B-cell lymphoma., Shaknovich, Rita, Geng Huimin, Johnson Nathalie A., Tsikitas Lucas, Cerchietti Leandro, Greally John M., Gascoyne Randy D., Elemento Olivier, and Melnick Ari , Blood, 2010 Nov 18, Volume 116, Issue 20, p.e81-9, (2010)
Epigenetics and B-cell lymphoma., Shaknovich, Rita, and Melnick Ari , Curr Opin Hematol, 2011 Jul, Volume 18, Issue 4, p.293-9, (2011)
DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis., Shah, Mrinal Y., Vasanthakumar Aparna, Barnes Natalie Y., Figueroa Maria E., Kamp Anna, Hendrick Christopher, Ostler Kelly R., Davis Elizabeth M., Lin Shang, Anastasi John, et al. , Cancer Res, 2010 Jul 15, Volume 70, Issue 14, p.5840-50, (2010)
Emerging epigenetic-modulating therapies in lymphoma., Sermer, David, Pasqualucci Laura, Wendel Hans-Guido, Melnick Ari, and Younes Anas , Nat Rev Clin Oncol, 2019 Aug, Volume 16, Issue 8, p.494-507, (2019)
Promoter hypermethylation in MLL-r infant acute lymphoblastic leukemia: biology and therapeutic targeting., Schafer, Eric, Irizarry Rafael, Negi Sandeep, McIntyre Emily, Small Donald, Figueroa Maria E., Melnick Ari, and Brown Patrick , Blood, 2010 Jun 10, Volume 115, Issue 23, p.4798-809, (2010)
IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics., Sasaki, Masato, Knobbe Christiane B., Munger Joshua C., Lind Evan F., Brenner Dirk, Brüstle Anne, Harris Isaac S., Holmes Roxanne, Wakeham Andrew, Haight Jillian, et al. , Nature, 2012 Aug 30, Volume 488, Issue 7413, p.656-9, (2012)
Epigenetics in focus: pathogenesis of myelodysplastic syndromes and the role of hypomethylating agents., Santini, Valeria, Melnick Ari, Maciejewski Jaroslaw P., Duprez Estelle, Nervi Clara, Cocco Lucio, Ford Kevin G., and Mufti Ghulam , Crit Rev Oncol Hematol, 2013 Nov, Volume 88, Issue 2, p.231-45, (2013)
Downregulation of FOXP1 is required during germinal center B-cell function., Sagardoy, Ainara, Martinez-Ferrandis Jose I., Roa Sergio, Bunting Karen L., Aznar María Angela, Elemento Olivier, Shaknovich Rita, Fontan Lorena, Fresquet Vicente, Perez-Roger Ignacio, et al. , Blood, 2013 May 23, Volume 121, Issue 21, p.4311-20, (2013)
Pathogenic role of B-cell receptor signaling and canonical NF-κB activation in mantle cell lymphoma., Saba, Nakhle S., Liu Delong, Herman Sarah E. M., Underbayev Chingiz, Tian Xin, Behrend David, Weniger Marc A., Skarzynski Martin, Gyamfi Jennifer, Fontan Lorena, et al. , Blood, 2016 07 07, Volume 128, Issue 1, p.82-92, (2016)
MALT1 Inhibition Is Efficacious in Both Naïve and Ibrutinib-Resistant Chronic Lymphocytic Leukemia., Saba, Nakhle S., Wong Deanna H., Tanios Georges, Iyer Jessica R., Lobelle-Rich Patricia, Dadashian Eman L., Liu Delong, Fontan Lorena, Flemington Erik K., Nichols Cydney M., et al. , Cancer Res, 2017 12 15, Volume 77, Issue 24, p.7038-7048, (2017)