Found 271 results
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A
ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression., Abdel-Wahab, Omar, Adli Mazhar, LaFave Lindsay M., Gao Jie, Hricik Todd, Shih Alan H., Pandey Suveg, Patel Jay P., Chung Young Rock, Koche Richard, et al. , Cancer Cell, 2012 Aug 14, Volume 22, Issue 2, p.180-93, (2012)
Targeted detection and quantitation of histone modifications from 1,000 cells., Abshiru, Nebiyu A., Sikora Jacek W., Camarillo Jeannie M., Morris Juliette A., Compton Philip D., Lee Tak, Neelamraju Yaseswini, Haddox Samuel, Sheridan Caroline, Carroll Martin, et al. , PLoS One, 2020, Volume 15, Issue 10, p.e0240829, (2020)
Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response., Agirre, Xabier, Meydan Cem, Jiang Yanwen, Garate Leire, Doane Ashley S., Li Zhuoning, Verma Akanksha, Paiva Bruno, Martín-Subero José I., Elemento Olivier, et al. , Nat Commun, 2019 02 18, Volume 10, Issue 1, p.821, (2019)
Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers., Agirre, Xabier, Castellano Giancarlo, Pascual Marien, Heath Simon, Kulis Marta, Segura Victor, Bergmann Anke, Esteve Anna, Merkel Angelika, Raineri Emanuele, et al. , Genome Res, 2015 Apr, Volume 25, Issue 4, p.478-87, (2015)
Mechanism of SMRT corepressor recruitment by the BCL6 BTB domain., K Ahmad, Farid, Melnick Ari, Lax Stuart, Bouchard Denis, Liu Jun, Kiang Chih-Li, Mayer Sebastian, Takahashi Shinichiro, Licht Jonathan D., and Prive Gilbert G. , Mol Cell, 2003 Dec, Volume 12, Issue 6, p.1551-64, (2003)
methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles., Akalin, Altuna, Kormaksson Matthias, Li Sheng, Garrett-Bakelman Francine E., Figueroa Maria E., Melnick Ari, and Mason Christopher E. , Genome Biol, 2012 Oct 03, Volume 13, Issue 10, p.R87, (2012)
Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia., Akalin, Altuna, Garrett-Bakelman Francine E., Kormaksson Matthias, Busuttil Jennifer, Zhang Lu, Khrebtukova Irina, Milne Thomas A., Huang Yongsheng, Biswas Debabrata, Hess Jay L., et al. , PLoS Genet, 2012, Volume 8, Issue 6, p.e1002781, (2012)
C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia., Alberich-Jorda, Meritxell, Wouters Bas, Balastik Martin, Shapiro-Koss Clara, Zhang Hong, Di Ruscio Annalisa, Radomska Hanna S., Ebralidze Alexander K., Amabile Giovanni, Ye Min, et al. , J Clin Invest, 2012 Dec, Volume 122, Issue 12, p.4490-504, (2012)
Widespread hypomethylation occurs early and synergizes with gene amplification during esophageal carcinogenesis., Alvarez, Hector, Opalinska Joanna, Zhou Li, Sohal Davendra, Fazzari Melissa J., Yu Yiting, Montagna Christina, Montgomery Elizabeth A., Canto Marcia, Dunbar Kerry B., et al. , PLoS Genet, 2011 Mar, Volume 7, Issue 3, p.e1001356, (2011)
How Biophysical Forces Regulate Human B Cell Lymphomas., Apoorva, F, Loiben Alexander M., Shah Shivem B., Purwada Alberto, Fontan Lorena, Goldstein Rebecca, Kirby Brian J., Melnick Ari M., Cosgrove Benjamin D., and Singh Ankur , Cell Rep, 2018 Apr 10, Volume 23, Issue 2, p.499-511, (2018)
B
The promyelocytic leukemia zinc finger (PLZF) protein binds DNA in a high molecular weight complex associated with cdc2 kinase., Ball, H J., Melnick A, Shaknovich R, Kohanski R A., and Licht J D. , Nucleic Acids Res, 1999 Oct 15, Volume 27, Issue 20, p.4106-13, (1999)
The Bcl6-SMRT/NCoR cistrome represses inflammation to attenuate atherosclerosis., Barish, Grant D., Yu Ruth T., Karunasiri Malith S., Becerra Diana, Kim Jason, Tseng Tiffany W., Tai Li-Jung, Leblanc Matthias, Diehl Cody, Cerchietti Leandro, et al. , Cell Metab, 2012 Apr 04, Volume 15, Issue 4, p.554-62, (2012)
HSC commitment-associated epigenetic signature is prognostic in acute myeloid leukemia., Bartholdy, Boris, Christopeit Maximilian, Will Britta, Mo Yongkai, Barreyro Laura, Yu Yiting, Bhagat Tushar D., Okoye-Okafor Ujunwa C., Todorova Tihomira I., Greally John M., et al. , J Clin Invest, 2014 Mar, Volume 124, Issue 3, p.1158-67, (2014)
Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas., Bayliss, Jill, Mukherjee Piali, Lu Chao, Jain Siddhant U., Chung Chan, Martinez Daniel, Sabari Benjamin, Margol Ashley S., Panwalkar Pooja, Parolia Abhijit, et al. , Sci Transl Med, 2016 11 23, Volume 8, Issue 366, p.366ra161, (2016)
EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation., Béguelin, Wendy, Popovic Relja, Teater Matt, Jiang Yanwen, Bunting Karen L., Rosen Monica, Shen Hao, Yang Shao Ning, Wang Ling, Ezponda Teresa, et al. , Cancer Cell, 2013 May 13, Volume 23, Issue 5, p.677-92, (2013)
EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop., Béguelin, Wendy, Rivas Martín A., Fernández María T. Calvo, Teater Matt, Purwada Alberto, Redmond David, Shen Hao, Challman Matt F., Elemento Olivier, Singh Ankur, et al. , Nat Commun, 2017 10 12, Volume 8, Issue 1, p.877, (2017)
Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response., Béguelin, Wendy, Teater Matt, Meydan Cem, Hoehn Kenneth B., Phillip Jude M., Soshnev Alexey A., Venturutti Leandro, Rivas Martín A., Calvo-Fernández María T., Gutierrez Johana, et al. , Cancer Cell, 2020 05 11, Volume 37, Issue 5, p.655-673.e11, (2020)
EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis., Béguelin, Wendy, Teater Matt, Gearhart Micah D., Fernández María Teresa Cal, Goldstein Rebecca L., Cardenas Mariano G., Hatzi Katerina, Rosen Monica, Shen Hao, Corcoran Connie M., et al. , Cancer Cell, 2016 08 08, Volume 30, Issue 2, p.197-213, (2016)
LITAF, a BCL6 target gene, regulates autophagy in mature B-cell lymphomas., Bertolo, Cristina, Roa Sergio, Sagardoy Ainara, Mena-Varas Maria, Robles Eloy F., Martinez-Ferrandis Jose I., Sagaert Xavier, Tousseyn Thomas, Orta Alberto, Lossos Izidore S., et al. , Br J Haematol, 2013 Sep, Volume 162, Issue 5, p.621-30, (2013)
Cell-free DNA (cfDNA) and Exosome Profiling from a Year-Long Human Spaceflight Reveals Circulating Biomarkers., Bezdan, Daniela, Grigorev Kirill, Meydan Cem, Vatter Fanny A. Pelissie, Cioffi Michele, Rao Varsha, MacKay Matthew, Nakahira Kiichi, Burnham Philip, Afshinnekoo Ebrahim, et al. , iScience, 2020 Dec 18, Volume 23, Issue 12, p.101844, (2020)
VII. Are lymphomas driven by epigenetic lesions?, Boss, Isaac W., and Melnick Ari M. , Hematol Oncol, 2015 Jun, Volume 33 Suppl 1, p.42-5, (2015)
MEF2C Phosphorylation Is Required for Chemotherapy Resistance in Acute Myeloid Leukemia., Brown, Fiona C., Still Eric, Koche Richard P., Yim Christina Y., Takao Sumiko, Cifani Paolo, Reed Casie, Gunasekera Shehana, Ficarro Scott B., Romanienko Peter, et al. , Cancer Discov, 2018 04, Volume 8, Issue 4, p.478-497, (2018)
Identification of FOXM1 as a therapeutic target in B-cell lineage acute lymphoblastic leukaemia., Buchner, Maike, Park Eugene, Geng Huimin, Klemm Lars, Flach Johanna, Passegué Emmanuelle, Schjerven Hilde, Melnick Ari, Paietta Elisabeth, Kopanja Dragana, et al. , Nat Commun, 2015 Mar 10, Volume 6, p.6471, (2015)
New effector functions and regulatory mechanisms of BCL6 in normal and malignant lymphocytes., Bunting, Karen L., and Melnick Ari M. , Curr Opin Immunol, 2013 Jun, Volume 25, Issue 3, p.339-46, (2013)
Multi-tiered Reorganization of the Genome during B Cell Affinity Maturation Anchored by a Germinal Center-Specific Locus Control Region., Bunting, Karen L., T Soong David, Singh Rajat, Jiang Yanwen, Béguelin Wendy, Poloway David W., Swed Brandon L., Hatzi Katerina, Reisacher William, Teater Matt, et al. , Immunity, 2016 09 20, Volume 45, Issue 3, p.497-512, (2016)